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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHTF18
All Species:
26.67
Human Site:
Y177
Identified Species:
45.13
UniProt:
Q8WVB6
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVB6
NP_071375.1
975
107383
Y177
R
P
P
I
L
E
D
Y
V
H
V
T
S
T
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087813
975
107675
Y177
R
P
P
I
L
E
D
Y
V
H
V
T
S
T
E
Dog
Lupus familis
XP_547205
952
105405
A151
T
S
T
A
G
S
R
A
F
L
V
L
R
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIW9
969
108119
Y173
R
P
P
I
L
E
D
Y
I
N
V
T
S
T
S
Rat
Rattus norvegicus
NP_001099243
968
107973
Y171
R
P
P
V
L
E
D
Y
I
N
V
T
S
T
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519056
506
55652
Chicken
Gallus gallus
XP_414833
951
106607
Y168
R
P
P
I
L
G
D
Y
I
N
V
T
S
S
E
Frog
Xenopus laevis
Q6NU40
1000
113204
Y195
R
P
P
V
L
E
D
Y
I
N
V
T
S
T
D
Zebra Danio
Brachydanio rerio
NP_001103572
957
108656
Y180
R
P
P
A
I
G
D
Y
I
T
V
T
D
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_787969
993
111731
R204
E
R
I
L
E
L
R
R
K
M
R
E
S
S
K
Honey Bee
Apis mellifera
XP_001122463
755
86984
I103
Y
D
E
L
F
G
D
I
S
D
M
L
D
I
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780624
1005
112781
S186
T
R
Q
P
E
G
E
S
M
K
V
T
G
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_171966
954
107988
G161
F
P
I
T
A
P
D
G
G
D
R
V
Y
A
K
Baker's Yeast
Sacchar. cerevisiae
P49956
741
84355
D88
I
N
I
N
Y
L
L
D
K
I
E
A
S
G
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.5
73
N.A.
76
77.2
N.A.
20.2
53.7
53.4
46.6
N.A.
32.4
27.8
N.A.
34.6
Protein Similarity:
100
N.A.
95.9
79.6
N.A.
81.7
82.7
N.A.
29.8
68.7
71
63.3
N.A.
52.5
45.3
N.A.
54.1
P-Site Identity:
100
N.A.
100
6.6
N.A.
80
73.3
N.A.
0
73.3
73.3
46.6
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
N.A.
100
13.3
N.A.
93.3
93.3
N.A.
0
93.3
100
66.6
N.A.
26.6
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
39.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
8
0
0
8
0
0
0
8
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
0
0
0
0
65
8
0
15
0
0
15
0
29
% D
% Glu:
8
0
8
0
15
36
8
0
0
0
8
8
0
0
22
% E
% Phe:
8
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
29
0
8
8
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% H
% Ile:
8
0
22
29
8
0
0
8
36
8
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
15
8
0
0
0
0
15
% K
% Leu:
0
0
0
15
43
15
8
0
0
8
0
15
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
8
8
0
0
0
8
% M
% Asn:
0
8
0
8
0
0
0
0
0
29
0
0
0
0
8
% N
% Pro:
0
58
50
8
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
50
15
0
0
0
0
15
8
0
0
15
0
8
0
0
% R
% Ser:
0
8
0
0
0
8
0
8
8
0
0
0
58
29
8
% S
% Thr:
15
0
8
8
0
0
0
0
0
8
0
58
0
36
0
% T
% Val:
0
0
0
15
0
0
0
0
15
0
65
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
50
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _